Efficacy of once‐weekly insulin efsitora versus once‐daily basal insulin in type 2 diabetes: A systematic review and meta‐analysis

Once-weekly insulin efsitora demonstrated comparable glycaemic efficacy and superiority in reduction of HbA1c and change in total weekly insulin dose at 52 weeks, while maintaining an acceptable safety profile. Longer-term studies and real-world data are warranted to further confirm sustained efficacy, safety, and cost-effectiveness.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-01-19
DOI
https://doi.org/10.1111/dom.70399
Primary Topic
Diabetes Management and Research
Type
article
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article

Efficacy of once‐weekly insulin efsitora versus once‐daily basal insulin in type 2 diabetes: A systematic review and meta‐analysis

Sheharyar Tariq, Minahil Iqbal, Aleena Iqbal, Mohsan Mustafa et al.
Diabetes Obesity and Metabolism
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article

Efficacy of once‐weekly insulin efsitora versus once‐daily basal insulin in type 2 diabetes: A systematic review and meta‐analysis

Sheharyar Tariq, Minahil Iqbal, Aleena Iqbal, Mohsan Mustafa, Furqan Ahmad Sethi, Mariam Akmal, Jannat Fatima, Rumaisa Riaz, Areeba Akmal, Sufyan Shahid, Gulraiz Gulzar
article en

Abstract

Once-weekly insulin efsitora demonstrated comparable glycaemic efficacy and superiority in reduction of HbA1c and change in total weekly insulin dose at 52 weeks, while maintaining an acceptable safety profile. Longer-term studies and real-world data are warranted to further confirm sustained efficacy, safety, and cost-effectiveness.

Diabetes Obesity and MetabolismVol. 28(3)
Khyber Medical College (PK), Allama Iqbal Medical College (PK), CMH Lahore Medical College and Institute of Dentistry (PK), Dow University of Health Sciences (PK), University of Gujrat (PK)
Openalex Percentile: Top 85%
Diabetes Management and Research
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