Exploring the incidence and influencing factors of acute gastrointestinal injury in ICU patients undergoing mechanical ventilation: a retrospective cohort study

During the study period, 425 patients with a median age of 60 years (interquartile range, 48-70), including 290 males (68%), received IMV during their ICU stay. AGI occurred in 287 patients, with an incidence rate of 67.5%. The most common symptom of AGI was gastric retention (50.52%). Multivariate regression analysis results showed the following as risk factors for AGI: the administration of catecholamine drugs (OR: 2.881, 95% CI 1.525 to 5.441, P = 0.001), Acute Physiology and Chronic Health Evaluation II score (OR: 1.119, 95% CI 1.055 to 1.186, P < 0.001), Nutritional Risk Screening 2002 score (OR: 1.416, 95% CI 1.154 to 1.737, P = 0.001), duration of IMV (OR: 1.142, 95% CI 1.108 to 1.207, P < 0.001), and primary disease involving the respiratory system (OR: 2.097, 95% CI 1.179 to 3.731, P = 0.012).