Chromatin remodeling by HIRA and FAS2 restricts geminivirus pathogenesis in plants
Overexpression of NbHIRA and NbFAS2 significantly boosts antiviral activity against geminivirus infections by altering the structure of virus minichromosomes. Consequently, these findings propose that targeting histone chaperones such as NbHIRA and NbFAS2 could offer a promising strategy for managing geminivirus-related infections in crop plants and agricultural applications.
Authors
- Neha Gupta (ORCID: https://orcid.org/0000-0001-7234-3158)
- Shirin Sultana (ORCID: https://orcid.org/0000-0002-6747-584X)
- Supriya Chakraborty
Institutions
- Jawaharlal Nehru University (IN)
Publication Details
- Journal
- Virology Journal
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1186/s12985-026-03068-7
- Primary Topic
- Plant Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00