Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines
Our results indicate a role of HMGA2 in the EC, because its inhibition reduces cell malignant characteristics, and may represent a viable therapeutic target to improve the prognosis of CisR TGCTs.
Authors
- Alfredo Fusco (ORCID: https://orcid.org/0000-0003-3332-5197)
- Marco Barchi (ORCID: https://orcid.org/0000-0003-1104-6234)
- Francesco Esposito (ORCID: https://orcid.org/0000-0002-7709-5736)
- Paolo Chieffi (ORCID: https://orcid.org/0000-0001-8483-5635)
- Matteo Lampitto (ORCID: https://orcid.org/0009-0005-7035-0713)
- Marco De Martino
Institutions
- University of Rome Tor Vergata (IT)
- Bedër University (AL)
- University of Campania "Luigi Vanvitelli" (IT)
- Institute for Experimental Endocrinology and Oncology (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Andrology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1111/andr.70177
- Citations
- 1
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 22.24