Vacuum-assisted breast biopsy vs core needle biopsy: a systematic review and meta-analysis

QuestionWhat is the diagnostic performance of VABB vs CNB in assessing suspicious breast lesions, including those with and without calcifications? FindingsMeta-analysis results showed a significantly lower risk for DCIS underestimation, ADH underestimation, and repeat biopsies using any imaging-guided VABB compared to imaging-guided CNB. Clinical relevanceVABB, as a first-line diagnostic procedure, is superior to CNB in terms of delivering a definitive diagnosis and reducing upgrade rates to malignancy, delivering a safe and efficient patient workflow.