Diffuse lipomatosis of the thyroid and thyroid papillary carcinoma, lipomatous type: A case report

Diffuse lipomatosis, characterized by the widespread presence of mature adipose tissue within the thyroid, is a rare condition. The presence of adipose tissue may vary within the neoplastic nodules in cases of diffuselipomatosis. Although the etiology remains unclear, it is generally regarded as an embryological developmental anomaly. This case report presents a 68-year-old female patient presented to the Ear, Nose, and Throat (ENT) clinic with complaints of neck swelling. Ultrasonographic examination revealed an enlarged thyroid gland and a 2 cm nodule. The patient subsequently underwent the left lobectomy. Histological examination of the thyroid tissue showed diffuse lipomatosis and thyroid papillary carcinoma with adipose tissue in the stroma. In pathology practice, the presence of adipose tissue in the thyroid is a rare finding that can occur in both benign and malignant neoplasms.

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Publication Details

Journal
Indian Journal of Pathology and Microbiology
Published
2026-01-19
DOI
https://doi.org/10.4103/ijpm.ijpm_276_25
Primary Topic
Body Contouring and Surgery
Type
article
Field-Weighted Citation Impact
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article

Diffuse lipomatosis of the thyroid and thyroid papillary carcinoma, lipomatous type: A case report

Ali Mızrak
Indian Journal of Pathology and Microbiology
Body Contouring and Surgery
article

Diffuse lipomatosis of the thyroid and thyroid papillary carcinoma, lipomatous type: A case report

Ali Mızrak
article en

Abstract

Diffuse lipomatosis, characterized by the widespread presence of mature adipose tissue within the thyroid, is a rare condition. The presence of adipose tissue may vary within the neoplastic nodules in cases of diffuselipomatosis. Although the etiology remains unclear, it is generally regarded as an embryological developmental anomaly. This case report presents a 68-year-old female patient presented to the Ear, Nose, and Throat (ENT) clinic with complaints of neck swelling. Ultrasonographic examination revealed an enlarged thyroid gland and a 2 cm nodule. The patient subsequently underwent the left lobectomy. Histological examination of the thyroid tissue showed diffuse lipomatosis and thyroid papillary carcinoma with adipose tissue in the stroma. In pathology practice, the presence of adipose tissue in the thyroid is a rare finding that can occur in both benign and malignant neoplasms.

Indian Journal of Pathology and Microbiology
Haseki Eğitim ve Araştırma Hastanesi (TR)
Gender equality
Openalex Percentile: Top 84%
Body Contouring and Surgery
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