Incidental Finding in Histopathology Report of Unnatural Deaths: A Six-year Retrospective Study

Incidental histopathological findings during medicolegal autopsies provide valuable insights into the underlying health status of individuals who appear clinically healthy during life. Such findings contribute to understanding silent disease burdens in the community. A six-year retrospective study (2016–2021) was conducted at a tertiary care institute in Northeast India, analyzing medicolegal autopsy cases of apparently healthy individuals with no documented chronic illness who died due to unnatural causes. A total of 199 cases with significant incidental histopathological findings were included. Atherosclerosis was the most prevalent incidental finding (41%), followed by pulmonary edema (12%), diffuse alveolar damage (7%), interstitial pneumonitis (6%), and viral hepatitis (5%). The highest frequency of incidental lesions was observed in the 40–60-year age group. Notably, early atherosclerotic changes were identified even in individuals as young as 22 years. Although incidental findings did not contribute to the cause of death, they revealed a substantial burden of asymptomatic pathology in the population. These observations highlight the relevance of autopsy-based surveillance in understanding the epidemiology of silent diseases and their potential public health implications.

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Journal
Journal of Indian Academy of Forensic Medicine
Published
2025-12-01
DOI
https://doi.org/10.1177/09710973251409876
Primary Topic
Autopsy Techniques and Outcomes
Type
article
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article

Incidental Finding in Histopathology Report of Unnatural Deaths: A Six-year Retrospective Study

Konsam Suken Singh, Madhubala Devi, Soreingam Ragui A, M Bapin Kumar et al.
Journal of Indian Academy of Forensic Medicine
Autopsy Techniques and Outcomes
article

Incidental Finding in Histopathology Report of Unnatural Deaths: A Six-year Retrospective Study

Konsam Suken Singh, Madhubala Devi, Soreingam Ragui A, M Bapin Kumar, Gangmei Angam, Romen Shinglai
article en

Abstract

Incidental histopathological findings during medicolegal autopsies provide valuable insights into the underlying health status of individuals who appear clinically healthy during life. Such findings contribute to understanding silent disease burdens in the community. A six-year retrospective study (2016–2021) was conducted at a tertiary care institute in Northeast India, analyzing medicolegal autopsy cases of apparently healthy individuals with no documented chronic illness who died due to unnatural causes. A total of 199 cases with significant incidental histopathological findings were included. Atherosclerosis was the most prevalent incidental finding (41%), followed by pulmonary edema (12%), diffuse alveolar damage (7%), interstitial pneumonitis (6%), and viral hepatitis (5%). The highest frequency of incidental lesions was observed in the 40–60-year age group. Notably, early atherosclerotic changes were identified even in individuals as young as 22 years. Although incidental findings did not contribute to the cause of death, they revealed a substantial burden of asymptomatic pathology in the population. These observations highlight the relevance of autopsy-based surveillance in understanding the epidemiology of silent diseases and their potential public health implications.

Journal of Indian Academy of Forensic MedicineVol. 47(4)
SMS Medical College (IN), Manipur University (IN), Regional Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 28%
Autopsy Techniques and Outcomes
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Incidental Finding in Histopathology Report of Unnatural Deaths: A Six-year Retrospective Study — Konsam Suken Singh, Madhubala Devi, et al. · Journal of Indian Academy of Forensic Medicine (2025) | TGRS Research Map | TGRS