Multiple orthokeratinized odontogenic cysts - A case report

Orthokeratinized odontogenic cysts (OOC) are uncommon developmental odontogenic cysts of jaw. It was previously considered as an orthokeratinized variant of Odontogenic keratocyst (OKC). OOC differs from OKC of its clinical and histological behavior. A 34-year-old male came for replacement of missing teeth in the right side of lower jaw. History revealed extraction of 46, 47, 48, and enucleation of cyst 15 years before for a radiolucent lesion of right posterior region, which was histologically diagnosed as orthokeratinized variant of OKC. On a radiographic evaluation, unilocular radiolucency was evident in the left posterior mandible and right maxillary anterior region that were clinically diagnosed as OKC in posterior mandible and dentigerous cyst in anterior maxilla in relation to impacted 13. Histologically, both the lesions showed a thin and uniform thickness of orthokeratinized stratified squamous epithelium with abundant keratin in the lumen. The case was diagnosed as Multiple OOC.