ASB5 is a specific marker for muscle satellite cells but dispensable for skeletal muscle development and regeneration
These data together identify ASB5 as an abundantly expressed and specific marker of MuSCs and myogenic progenitors. However, Asb5 loss-of-function has no effects on embryonic development and postnatal growth of skeletal muscles, or behavior and regenerative functions of MuSCs under normal physiological conditions.
Authors
- Muhammad Asif (ORCID: https://orcid.org/0000-0002-6083-8345)
- Stephanie N. Oprescu
- Renjie Shang (ORCID: https://orcid.org/0000-0002-9184-4094)
- Pengpeng Bi (ORCID: https://orcid.org/0000-0002-9871-6773)
- Kuang Shihuan
- Feng Yue
- Zheng Zhang
Institutions
- University of Georgia (US)
- Duke University (US)
- Purdue University West Lafayette (US)
- University of Florida (US)
- Duke Medical Center (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Skeletal Muscle
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1186/s13395-025-00409-y
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00