Meconium Periorchitis

Meconium periorchitis (MPO) is an unusual entity that presents as a scrotal mass in the early neonatal period and is seen in 1 in 30,000 live births. MPO is associated with meconium peritonitis, that leads to leakage of sterile meconium through patent processus vaginalis into the developing scrotum. Clinically, this entity presents as a para-testicular mass which shows scattered calcifications on imaging, thus warranting diagnostic work up and histopathological confirmation. Our case is an 8 month-old male baby with a firm to hard scrotal cyst. Intraoperatively, a diagnosis of teratoma was considered due to the complex solid cystic nature of the lesion and it was excised. Histology confirmed the diagnosis of MPO. Although some cases of MPO show spontaneous regression, about 65% warrant a surgical intervention. However, lack of awareness of this entity can lead to unnecessary orchiectomy.

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Publication Details

Journal
Pediatric and Developmental Pathology
Published
2026-01-19
DOI
https://doi.org/10.1177/10935266251412516
Primary Topic
Intestinal Malrotation and Obstruction Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Meconium Periorchitis

Kiruthiga Kala Gnanasekaran, Dr Shashank Shrotriya, Sunil Chordia, Heena Shah et al.
Pediatric and Developmental Pathology
Intestinal Malrotation and Obstruction Disorders
article

Meconium Periorchitis

Kiruthiga Kala Gnanasekaran, Dr Shashank Shrotriya, Sunil Chordia, Heena Shah, Anusha Kulkarni, Priyanka Randive
article en

Abstract

Meconium periorchitis (MPO) is an unusual entity that presents as a scrotal mass in the early neonatal period and is seen in 1 in 30,000 live births. MPO is associated with meconium peritonitis, that leads to leakage of sterile meconium through patent processus vaginalis into the developing scrotum. Clinically, this entity presents as a para-testicular mass which shows scattered calcifications on imaging, thus warranting diagnostic work up and histopathological confirmation. Our case is an 8 month-old male baby with a firm to hard scrotal cyst. Intraoperatively, a diagnosis of teratoma was considered due to the complex solid cystic nature of the lesion and it was excised. Histology confirmed the diagnosis of MPO. Although some cases of MPO show spontaneous regression, about 65% warrant a surgical intervention. However, lack of awareness of this entity can lead to unnecessary orchiectomy.

Pediatric and Developmental Pathology
Aditya Birla Memorial Hospital (IN), College of Medicine & JNM Hospital (IN)
Good health and well-being
Openalex Percentile: Top 84%
Intestinal Malrotation and Obstruction Disorders
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