Characterization and <i>in planta</i> tolerance of a phosphinothricin acetyltransferase enzyme from <i>Streptomyces coelicolor</i> <scp>A3</scp> (2)

Here we show for the first time that when the DSM-2 trait is transgenically overexpressed in soybean and corn plants, it provides a similar level of herbicide tolerance as other previously characterized PAT or Bar enzymes. Protein structure modeling also supports the conclusion that DSM-2 is in the same protein family as PAT and Bar. As such, although DSM-2 shares little homology from a primary protein sequence standpoint, the trait is still a viable alternative for use in commercial herbicide tolerance programs. © 2026 Society of Chemical Industry.

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Publication Details

Journal
Pest Management Science
Published
2026-01-19
DOI
https://doi.org/10.1002/ps.70572
Primary Topic
Weed Control and Herbicide Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Characterization and in planta tolerance of a phosphinothricin acetyltransferase enzyme from Streptomyces coelicolor A3 (2)

Justin M. Lira, Kiheon Baek, Samantha L. Griffin, Jonathan P. DiNitto et al.
Pest Management Science
Weed Control and Herbicide Applications
article

Characterization and in planta tolerance of a phosphinothricin acetyltransferase enzyme from Streptomyces coelicolor A3 (2)

Justin M. Lira, Kiheon Baek, Samantha L. Griffin, Jonathan P. DiNitto, Kevin McGregor
article en

Abstract

Here we show for the first time that when the DSM-2 trait is transgenically overexpressed in soybean and corn plants, it provides a similar level of herbicide tolerance as other previously characterized PAT or Bar enzymes. Protein structure modeling also supports the conclusion that DSM-2 is in the same protein family as PAT and Bar. As such, although DSM-2 shares little homology from a primary protein sequence standpoint, the trait is still a viable alternative for use in commercial herbicide tolerance programs. © 2026 Society of Chemical Industry.

Pest Management Science
Corteva (United States) (US)
Openalex Percentile: Top 84%
Weed Control and Herbicide Applications
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