Impact of extracorporeal membrane oxygenation modes on voriconazole exposure in critically ill patients
ECMO support did not significantly reduce voriconazole Cmin compared with the non-ECMO group. However, VAV-ECMO is associated with reduced voriconazole exposure, suggesting a configuration-specific rather than uniform ECMO effect. Routine therapeutic drug monitoring remains essential.
Authors
- Xiao Tang (ORCID: https://orcid.org/0000-0003-2918-7748)
- Zhuoling An
- Haitao Zhang (ORCID: https://orcid.org/0000-0002-1639-4089)
- Bing Sun
- Shiyu Song
- Xinrui Wang
Institutions
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Beijing Anzhen Hospital (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1093/jac/dkaf501
- Primary Topic
- Nosocomial Infections in ICU
- Type
- article
- Field-Weighted Citation Impact
- 0.00