Tobacco advertising, cross-over effects, and US adolescent progression from never to current tobacco use

Among adolescents who were receptive to tobacco advertising but had never used tobacco at baseline, there was significant progression to current and daily tobacco use 6.6 years later. The cross-over advertising effect went beyond the particular advertised product and effectively promoted daily nicotine use, particularly among 12-14-year-old adolescents at baseline, with progression to e-cigarettes. Population increases in adolescent progression to daily nicotine use is a public health harm that needs public health action to counteract the effectiveness of e-cigarette marketing both in schools and at the community level.