Safety and efficacy of gepotidacin in urinary tract infection: a GRADE-assessed systematic review and meta-analysis
Gepotidacin provides superior composite and microbiological outcomes relative to nitrofurantoin for female uUTI but is associated with increased mild-to-moderate gastrointestinal toxicity. Long-term tolerability and resistance surveillance are recommended.
Authors
- Amjad Ali (ORCID: https://orcid.org/0000-0001-9117-3692)
- Zain Ul Abideen Shahid (ORCID: https://orcid.org/0009-0007-2387-8472)
- Jawaria Ibrahim
- Faiqah Nizam
- Muhammad Burhan
- Taha Ibrahim
- Muhammad Abdullah Naveed
Institutions
- Hamdard University (PK)
- Jinnah Sindh Medical University (PK)
- Dow University of Health Sciences (PK)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1093/jac/dkaf469
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00