3D-Printed Titanium Cages for Anterior and Lateral Lumbar Interbody Fusion Result in Excellent Fusion Rates One Year After Surgery

Study Design: Retrospective study. Objective: To determine the fusion rate in patients undergoing anterior lumbar interbody fusion (ALIF) and/or lateral lumbar interbody fusion (LLIF) with titanium cages. Methods: Fusion at 1-year was assessed by computed tomography (CT) using Lenke-Bridwell classification. Flexion-extension lateral radiographs confirmed fusion if motion was <5° through the fused segment. Perioperative metrics including bone graft type, operative time, estimated blood loss, revisions within the first postoperative year, clinical outcome assessed by the Oswestry Disability Index (ODI). Results: One hundred patients with a total of 137 fusion levels with 3DPTi cages were identified. In this cohort, 75% underwent primary surgery and 25% had a previous surgery. At 1-year post-op, 97.1% of interbody levels were fused (Grade I) on CT, and all levels appeared fused on flexion-extension radiographs. Four patients (4%) required additional surgery within the first two years. No revisions were required for cage subsidence/migration, or pseudoarthrosis. Median ODI significantly improved from 39 at baseline to 10 at 1-year ( = .001). Conclusion: 3D-printed titanium cages for ALIF and LLIF result in excellent fusion rates at one year postoperatively without the use of rhBMP-2.

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Publication Details

Journal
Universität Zürich, ZORA
Published
2025-06-01
DOI
https://doi.org/10.5167/uzh-282956
Primary Topic
Spine and Intervertebral Disc Pathology
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article
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article

3D-Printed Titanium Cages for Anterior and Lateral Lumbar Interbody Fusion Result in Excellent Fusion Rates One Year After Surgery

Anna-Katharina Calek, Aaron J Buckland, Bettina Hochreiter
Universität Zürich, ZORA
Spine and Intervertebral Disc Pathology
article

3D-Printed Titanium Cages for Anterior and Lateral Lumbar Interbody Fusion Result in Excellent Fusion Rates One Year After Surgery

Anna-Katharina Calek, Aaron J Buckland, Bettina Hochreiter
article en

Abstract

Study Design: Retrospective study. Objective: To determine the fusion rate in patients undergoing anterior lumbar interbody fusion (ALIF) and/or lateral lumbar interbody fusion (LLIF) with titanium cages. Methods: Fusion at 1-year was assessed by computed tomography (CT) using Lenke-Bridwell classification. Flexion-extension lateral radiographs confirmed fusion if motion was <5° through the fused segment. Perioperative metrics including bone graft type, operative time, estimated blood loss, revisions within the first postoperative year, clinical outcome assessed by the Oswestry Disability Index (ODI). Results: One hundred patients with a total of 137 fusion levels with 3DPTi cages were identified. In this cohort, 75% underwent primary surgery and 25% had a previous surgery. At 1-year post-op, 97.1% of interbody levels were fused (Grade I) on CT, and all levels appeared fused on flexion-extension radiographs. Four patients (4%) required additional surgery within the first two years. No revisions were required for cage subsidence/migration, or pseudoarthrosis. Median ODI significantly improved from 39 at baseline to 10 at 1-year ( = .001). Conclusion: 3D-printed titanium cages for ALIF and LLIF result in excellent fusion rates at one year postoperatively without the use of rhBMP-2.

Universität Zürich, ZORA
Openalex Percentile: Top 27%
Spine and Intervertebral Disc Pathology
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3D-Printed Titanium Cages for Anterior and Lateral Lumbar Interbody Fusion Result in Excellent Fusion Rates One Year After Surgery — Anna-Katharina Calek, Aaron J Buckland, et al. · Universität Zürich, ZORA (2025) | TGRS Research Map | TGRS