AQP7 suppresses cell stemness and metastasis by targeting Wnt signaling in basal-like breast cancer
The current study demonstrates a tumor-suppressive function of AQP7 in breast cancer through inhibiting the cell cycle, EMT, and cancer cell stemness. AQP7 holds potential as a therapeutic target to treat breast cancer.
Authors
- X B Liu
- Zuoren Yu (ORCID: https://orcid.org/0000-0003-0800-5685)
- Jinhui Lü (ORCID: https://orcid.org/0000-0002-1481-8896)
- Danni Li (ORCID: https://orcid.org/0009-0007-5224-8082)
- Jinli Gao
- Qian Zhao
- William C Cho
- Yingjun Liao
- Yu Liu
Institutions
- Tongji University (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Expert Opinion on Therapeutic Targets
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1080/14728222.2026.2619758
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00