Unraveling the impact of loneliness on brain and emotion: exploring pathways for meaningful interventions

This paper aims to understand and explore the complex connections between loneliness, brain functions, the emotional regulations, along with the effects of loneliness on the brain and emotions. Besides, this study is addressing its implications for mental health and potential intervention strategies. The definition of loneliness is concluded as a subjective experience of social isolation, which has profound effects on the neural processes and impaired social cognition. Key findings of this paper have highlighted the role of stress-related neuropeptides and decreased activity in emotional processing regions such as the amygdala and impaired social cognition. This paper also reviews and examines potential interventions including mindfulness practices, social cognitive training, and community training that showed promising effects on mitigating loneliness. It is further explained by the integration of physiological psychology along with Islamic perspectives to emphasize the spiritual practices, feeling of gratitude, and social bonds in fostering emotional resilience for individuals. This study emphasizes the importance of holistic approaches to convey loneliness of individuals and even at the societal levels as well as offering such valuable implications for mental health practitioners.

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Publication Details

Journal
Scientific Repository (Petra Christian University)
Published
2025-12-31
Primary Topic
Mindfulness and Compassion Interventions
Type
article
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article

Unraveling the impact of loneliness on brain and emotion: exploring pathways for meaningful interventions

Usman Jaffer, Rahmah Ahmad H.Osman, ⁠Nur Amirah Husna Ahmad, Mohamed Ayaaz Ahmed et al.
Scientific Repository (Petra Christian University)
Mindfulness and Compassion Interventions
article

Unraveling the impact of loneliness on brain and emotion: exploring pathways for meaningful interventions

Usman Jaffer, Rahmah Ahmad H.Osman, ⁠Nur Amirah Husna Ahmad, Mohamed Ayaaz Ahmed, Nur Qistina Zahirah Amran, Che Mohd Nasril Che Mohd Nassir, Huriyyah Hamiemah Md Tajudin, Nurfahirah Irdina Ahmad Razif, Alya Qistina Norshamsul Alya Qistina Norshamsul Azmi, Nor Wadiah Zulkifli
article en

Abstract

This paper aims to understand and explore the complex connections between loneliness, brain functions, the emotional regulations, along with the effects of loneliness on the brain and emotions. Besides, this study is addressing its implications for mental health and potential intervention strategies. The definition of loneliness is concluded as a subjective experience of social isolation, which has profound effects on the neural processes and impaired social cognition. Key findings of this paper have highlighted the role of stress-related neuropeptides and decreased activity in emotional processing regions such as the amygdala and impaired social cognition. This paper also reviews and examines potential interventions including mindfulness practices, social cognitive training, and community training that showed promising effects on mitigating loneliness. It is further explained by the integration of physiological psychology along with Islamic perspectives to emphasize the spiritual practices, feeling of gratitude, and social bonds in fostering emotional resilience for individuals. This study emphasizes the importance of holistic approaches to convey loneliness of individuals and even at the societal levels as well as offering such valuable implications for mental health practitioners.

Scientific Repository (Petra Christian University)
Reduced inequalities
Openalex Percentile: Top 24%
Mindfulness and Compassion Interventions
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