Memory and learning deficiencies in Parkinson’s disease: understanding cognitive challenges and interventions

Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms and cognitive impairments, particularly in memory and learning. These impairments significantly affect the patients’ quality of life and people around them. Based on the past studies, aging, genetics and environment are expected to be some of the contributing factors in Parkison’s disease. Cognitive impairments in PD commonly caused by neurochemical or structural changes in the brains, which decrease dopaminergic neurons in substantia Nigra pars compacta (SNpc). Furthermore, this paper explores various cognitive domains including memory, learning and other executive functions in order to understand the extent of impairment that is experienced by people with Parkinson’s disease. However, despite the extensive study on PD, current interventions demonstrate lack of effectiveness in eradicating the issue of cognitive deficiency especially on learning and memory impairment. Hence, the paper discusses current interventions by addressing and applying the reviewed literature, ranging from pharmacological treatments to lifestyle modifications aimed at mitigating cognitive decline. This study also provides a comprehensive overview of suggestions for future research about PD. Lastly, from Islamic perspective, there is a hadith that encourages seeking medical treatment while integrating it with spiritual practices, such as Qur’anic recitation, to alleviate cognitive impairments. Listening to, reciting, and memorizing the Qur’an have been shown to enhance concentration, promote neuroplasticity, delay cognitive aging and improve memory, which can help mitigate the effects of PD.

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Publication Details

Journal
The International Islamic University Malaysia Repository (The International Islamic University Malaysia)
Published
2025-12-31
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
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article

Memory and learning deficiencies in Parkinson’s disease: understanding cognitive challenges and interventions

Mohamed Ayaaz Ahmed, Usman Jaffer, Nurul Syuhadah Fitri Suhaimi, Che Mohd Nasril Che Mohd Nassir et al.
The International Islamic University Malaysia Repository (The International Islamic University Malaysia)
Parkinson's Disease Mechanisms and Treatments
article

Memory and learning deficiencies in Parkinson’s disease: understanding cognitive challenges and interventions

Mohamed Ayaaz Ahmed, Usman Jaffer, Nurul Syuhadah Fitri Suhaimi, Che Mohd Nasril Che Mohd Nassir, ‘Alia Nabila Hairul Anuar, Tihani Husna Khairuddin, Huriyyah Hamiemah Md Tajudin, Nurfarah Nadhirah Azwan, Nur Radhna Sari Ruhaizad, Amirah Hannan Alaa Eldin Allam
article en

Abstract

Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms and cognitive impairments, particularly in memory and learning. These impairments significantly affect the patients’ quality of life and people around them. Based on the past studies, aging, genetics and environment are expected to be some of the contributing factors in Parkison’s disease. Cognitive impairments in PD commonly caused by neurochemical or structural changes in the brains, which decrease dopaminergic neurons in substantia Nigra pars compacta (SNpc). Furthermore, this paper explores various cognitive domains including memory, learning and other executive functions in order to understand the extent of impairment that is experienced by people with Parkinson’s disease. However, despite the extensive study on PD, current interventions demonstrate lack of effectiveness in eradicating the issue of cognitive deficiency especially on learning and memory impairment. Hence, the paper discusses current interventions by addressing and applying the reviewed literature, ranging from pharmacological treatments to lifestyle modifications aimed at mitigating cognitive decline. This study also provides a comprehensive overview of suggestions for future research about PD. Lastly, from Islamic perspective, there is a hadith that encourages seeking medical treatment while integrating it with spiritual practices, such as Qur’anic recitation, to alleviate cognitive impairments. Listening to, reciting, and memorizing the Qur’an have been shown to enhance concentration, promote neuroplasticity, delay cognitive aging and improve memory, which can help mitigate the effects of PD.

The International Islamic University Malaysia Repository (The International Islamic University Malaysia)
Quality Education
Openalex Percentile: Top 28%
Parkinson's Disease Mechanisms and Treatments
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