The possible impact of levosimendan infusions on clinical course of heart failure: the results of the LEIA-HF study

In a selected group of stable ambulatory advanced HF (left ventricular ejection fraction ≤35%, New York Heart Association Classes III and IV) patients, repetitive levosimendan 24 h infusion might be an additional therapeutic option but observed deaths may raise its safety issue.

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Publication Details

Journal
ESC Heart Failure
Published
2026-01-13
DOI
https://doi.org/10.1093/eschf/xvag021
Primary Topic
Heart Failure Treatment and Management
Type
article
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article

The possible impact of levosimendan infusions on clinical course of heart failure: the results of the LEIA-HF study

Agnieszka Tycińska, Ewelina Kazimierczyk, Agata Bielecka‐Dąbrowa, Mariusz Gąsior et al.
ESC Heart Failure
Heart Failure Treatment and Management
article

The possible impact of levosimendan infusions on clinical course of heart failure: the results of the LEIA-HF study

Agnieszka Tycińska, Ewelina Kazimierczyk, Agata Bielecka‐Dąbrowa, Mariusz Gąsior, Remigiusz Kazimierczyk, Ewelina Rogalska, Marek Gierlotka, Klaudia Mickiewicz, Agnieszka Pawlak, Anna Szyszkowska, Franciszek Kukliński, Jacek Kubica, Ł Szarpak, A Południewska, W Wojakowski, J D Kasprzak, P Leszek, M Jaguszewski, A Imiela, J Nessler, T Fernandez-Moreno, E Straburzynska-Migaj
article en

Abstract

In a selected group of stable ambulatory advanced HF (left ventricular ejection fraction ≤35%, New York Heart Association Classes III and IV) patients, repetitive levosimendan 24 h infusion might be an additional therapeutic option but observed deaths may raise its safety issue.

ESC Heart FailureVol. 13(1)
John Paul II Catholic University of Lublin (PL), Poznan University of Medical Sciences (PL), Jagiellonian University (PL), Medical University of Białystok (PL), Medical University of Silesia (PL), University of Opole (PL), Medical University of Warsaw (PL), Nicolaus Copernicus University (PL), Memorial Hospital (US), Medical University of Lodz (PL), Ministry of Interior (IT), Ministry of Interior and Administration (PL), Institute of Cardiology (PL), Polish Mother’s Memorial Hospital Research Institute (PL), Ministerio del Interior (ES), Lux Research (United States) (US), Gdańsk Medical University (PL)
Good health and well-being
Openalex Percentile: Top 86%
Heart Failure Treatment and Management
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