Lack of Discernible Benefit of High-Dose Aspirin in the Treatment of Kawasaki Disease

In a retrospective single-center cohort study of 460 children with Kawasaki Disease, initial treatment with low-dose aspirin and intravenous immunoglobulin (IVIG) resulted in similar coronary artery outcomes and IVIG retreatment rates compared to high-dose aspirin and IVIG. These findings support consideration of low-dose aspirin for the management of acute-phase Kawasaki Disease.

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Publication Details

Journal
Journal of the Pediatric Infectious Diseases Society
Published
2026-01-13
DOI
https://doi.org/10.1093/jpids/piag002
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
Field-Weighted Citation Impact
0.00
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article

Lack of Discernible Benefit of High-Dose Aspirin in the Treatment of Kawasaki Disease

Shulman St, Kwang-Youn Kim, Huthaifah Khan, Lavina Thadani et al.
Journal of the Pediatric Infectious Diseases Society
Kawasaki Disease and Coronary Complications
article

Lack of Discernible Benefit of High-Dose Aspirin in the Treatment of Kawasaki Disease

Shulman St, Kwang-Youn Kim, Huthaifah Khan, Lavina Thadani, Anne Rowley
article en

Abstract

In a retrospective single-center cohort study of 460 children with Kawasaki Disease, initial treatment with low-dose aspirin and intravenous immunoglobulin (IVIG) resulted in similar coronary artery outcomes and IVIG retreatment rates compared to high-dose aspirin and IVIG. These findings support consideration of low-dose aspirin for the management of acute-phase Kawasaki Disease.

Journal of the Pediatric Infectious Diseases SocietyVol. 15(2)
Northwestern University (US), Lurie Children's Hospital (US), University of Missouri–Kansas City (US)
Good health and well-being
Openalex Percentile: Top 85%
Kawasaki Disease and Coronary Complications
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