Immune Checkpoint Inhibitor-Induced Rapid Decline in Hepatitis B Virus Markers Improves the Prognosis of Hepatitis B Virus–Related Hepatocellular Carcinoma Patients

ICIs demonstrate dual therapeutic effects in HBV-related HCC, significantly reducing multiple HBV markers while concurrently enhancing prognosis in combination with antiviral therapy, emphasizing the importance of sustained virological suppression for optimal HCC outcomes.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2026-01-13
DOI
https://doi.org/10.1093/infdis/jiag036
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Immune Checkpoint Inhibitor-Induced Rapid Decline in Hepatitis B Virus Markers Improves the Prognosis of Hepatitis B Virus–Related Hepatocellular Carcinoma Patients

Kunyuan Wang, DingLi Liu, Yabing Guo, Minghui Zhu et al.
The Journal of Infectious Diseases
Hepatitis B Virus Studies
article

Immune Checkpoint Inhibitor-Induced Rapid Decline in Hepatitis B Virus Markers Improves the Prognosis of Hepatitis B Virus–Related Hepatocellular Carcinoma Patients

Kunyuan Wang, DingLi Liu, Yabing Guo, Minghui Zhu, Ying Xia, Xiaoyun Hu, Huaiyu Chen, Rong Fan, Yun Zhu, Mengya Zang, Yujie Ran, Jie Chen, Fang Liu, Qi Li, Qian Zhao, Xiaowei Chen, Shuai Kang, Hongyan Liu, Ying Wang
article en

Abstract

ICIs demonstrate dual therapeutic effects in HBV-related HCC, significantly reducing multiple HBV markers while concurrently enhancing prognosis in combination with antiviral therapy, emphasizing the importance of sustained virological suppression for optimal HCC outcomes.

The Journal of Infectious Diseases
Ministry of Education of the People's Republic of China (CN), Guangdong Provincial Center for Disease Control and Prevention (CN), Southern Medical University (CN)
Openalex Percentile: Top 85%
Hepatitis B Virus Studies
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Immune Checkpoint Inhibitor-Induced Rapid Decline in Hepatitis B Virus Markers Improves the Prognosis of Hepatitis B Virus–Related Hepatocellular Carcinoma Patients — Kunyuan Wang, DingLi Liu, et al. · The Journal of Infectious Diseases (2026) | TGRS Research Map | TGRS