Comparison of the Friedewald, Sampson, and Martin Formulas with Direct Homogeneous Assay of Low-Density Lipoprotein Cholesterol in South American Patients
S-LDL-c, M-LDL-c, and ME-LDL-c showed better agreement with D-LDL-c than F-LDL-c in this South American population. LRP analysis suggests S-LDL-c may provide most accurate estimation vs gold standard BQ, particularly in hypertriglyceridemia. These findings support the adoption of newer equations in clinical practice.
Authors
- Darío Jacobsen (ORCID: https://orcid.org/0000-0002-8082-3538)
- Nahuel Fernández Machulsky (ORCID: https://orcid.org/0009-0008-2432-0806)
- Antonella Fochi
- Abi Cardozo Madaf
- Maria Eugenia Gomez
- Gabriela Berg
Institutions
- Universidad de Buenos Aires (AR)
- Instituto de Química y Fisicoquímica Biológicas (AR)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1093/jalm/jfaf204
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00