Sphingosine-1-phosphate regulates platelet fibrinogen binding via sphingosine-1-phosphate receptor type 4
These findings strongly suggest that S1P signaling via S1PR<sub>4</sub> acts as a negative regulator of fibrinogen binding in activated platelets.
Authors
- Celine Hähnel
- Tobias Schulze (ORCID: https://orcid.org/0000-0001-8602-8431)
- Felix Lührs (ORCID: https://orcid.org/0000-0002-9859-1245)
- Maurice Hannemann
- Jan Wesche (ORCID: https://orcid.org/0000-0001-5025-7355)
- Stephan Kersting
- Janik Riese
- Rhagavendra Palankar
Institutions
- Universitätsmedizin Greifswald (DE)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1016/j.jtha.2025.12.019
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00