Adults with anomalous aortic origin of a coronary artery: impact of invasive functional testing on clinical decision making—insights from the MuSCAT registry
This study in adult AAOCA patients revealed a 28% discrepancy between non-invasive and invasive functional testing, altering management recommendations for 20% of the overall cohort. Implementing optimal functional testing modalities may enhance risk stratification for ischaemic events and sudden cardiac death, enabling tailored treatment strategies for AAOCA patients. Further prospective research with long-term follow-up is needed to evaluate clinical outcomes.Registered in the Dutch Trial Register #NL8777; https://onderzoekmetmensen.nl/en.
Authors
- Mark G. Hazekamp (ORCID: https://orcid.org/0000-0002-3150-5007)
- H. Vliegen
- D. Koolbergen
- Peter Damman (ORCID: https://orcid.org/0000-0002-9284-7967)
- Philippine Kiès (ORCID: https://orcid.org/0000-0002-1283-1122)
- Anastasia D. Egorova (ORCID: https://orcid.org/0000-0001-9312-2338)
- Monique R M Jongbloed
- Michiel Voskuil (ORCID: https://orcid.org/0000-0003-1789-8462)
- Michael G. Dickinson (ORCID: https://orcid.org/0000-0003-1980-1919)
- Lodewijk J. Wagenaar
- Marco C. Post (ORCID: https://orcid.org/0009-0001-8404-1728)
- Marcel A M Beijk
- Robbert J de Winter
- J Wouter Jukema
- Frank van der Kley
- C J Koppel
- Diederick B H Verheijen
- Hildo J Lamb
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Medisch Spectrum Twente (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- St. Antonius Ziekenhuis (NL)
- Netherlands Heart Institute (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- European Heart Journal - Imaging Methods and Practice
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1093/ehjimp/qyag010
- Primary Topic
- Coronary Artery Anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00