Clinical Characteristics of Patients With Patent Foramen Ovale and Pyogenic Brain Abscess

Patent foramen ovale (PFO) has a prevalence of approximately 25%. Its association with pyogenic brain abscess (PBA) is unclear. We reviewed adults with PBA and known PFO status from 1 January 2009 through 31 December 2021 at Mayo Clinic. High PFO prevalence (40.5%) was seen. PBA patients with PFO had distinct abscess characteristics but unchanged 1-year, all-cause mortality.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2026-01-14
DOI
https://doi.org/10.1093/ofid/ofag026
Primary Topic
Cardiovascular and Diving-Related Complications
Type
article
Field-Weighted Citation Impact
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article

Clinical Characteristics of Patients With Patent Foramen Ovale and Pyogenic Brain Abscess

L.M. Baddour, GUY S. REEDER, Daniel Christopher DeSimone, Zachary A. Yetmar et al.
Open Forum Infectious Diseases
Cardiovascular and Diving-Related Complications
article

Clinical Characteristics of Patients With Patent Foramen Ovale and Pyogenic Brain Abscess

L.M. Baddour, GUY S. REEDER, Daniel Christopher DeSimone, Zachary A. Yetmar, Mark J. Enzler, Pansachee Damronglerd, Hussam Tabaja, Supavit Chesdachai, Khalid Abu-Zeinah, Cristina Corsini Campioli, Omar M Abu Saleh
article en

Abstract

Patent foramen ovale (PFO) has a prevalence of approximately 25%. Its association with pyogenic brain abscess (PBA) is unclear. We reviewed adults with PBA and known PFO status from 1 January 2009 through 31 December 2021 at Mayo Clinic. High PFO prevalence (40.5%) was seen. PBA patients with PFO had distinct abscess characteristics but unchanged 1-year, all-cause mortality.

Open Forum Infectious DiseasesVol. 13(2)
Thammasat University (TH), Cleveland Clinic (US), Mayo Clinic (US), Cleveland Foundation (US), Mayo Clinic Health System (US), Mayo Clinic in Florida (US)
Good health and well-being
Openalex Percentile: Top 86%
Cardiovascular and Diving-Related Complications
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Clinical Characteristics of Patients With Patent Foramen Ovale and Pyogenic Brain Abscess — L.M. Baddour, GUY S. REEDER, et al. · Open Forum Infectious Diseases (2026) | TGRS Research Map | TGRS