Unraveling Multi-target Mechanisms of Codonopsis pilosula in Breast Cancer: A Synergistic Approach Combining Network Pharmacology,Molecular Docking, and Machine Learning Techniques

This multidisciplinary, predictive strategy successfully identified key bioactive compounds in CP and their molecular targets in breast cancer. The study provides crucial mechanistic evidence for CP's therapeutic potential and highlights the power of this integrated approach for drug discovery from TCM (Traditional Chinese Medicine).

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Publication Details

Journal
Current Computer - Aided Drug Design
Published
2026-01-08
DOI
https://doi.org/10.2174/0115734099391503251119090622
Primary Topic
Computational Drug Discovery Methods
Type
article
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0.00
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article

Unraveling Multi-target Mechanisms of Codonopsis pilosula in Breast Cancer: A Synergistic Approach Combining Network Pharmacology,Molecular Docking, and Machine Learning Techniques

Haodong Guo, Jie Li, Fan Lin, Chunyan Hua et al.
Current Computer - Aided Drug Design
Computational Drug Discovery Methods
article

Unraveling Multi-target Mechanisms of Codonopsis pilosula in Breast Cancer: A Synergistic Approach Combining Network Pharmacology,Molecular Docking, and Machine Learning Techniques

Haodong Guo, Jie Li, Fan Lin, Chunyan Hua, Peiyun Zhong, Min Zheng, Wenqian Wang, Deqi Wang
article en

Abstract

This multidisciplinary, predictive strategy successfully identified key bioactive compounds in CP and their molecular targets in breast cancer. The study provides crucial mechanistic evidence for CP's therapeutic potential and highlights the power of this integrated approach for drug discovery from TCM (Traditional Chinese Medicine).

Current Computer - Aided Drug DesignVol. 22
Wenzhou Medical University (CN), Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 84%
Computational Drug Discovery Methods
DOISourceOpenAlex
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Unraveling Multi-target Mechanisms of Codonopsis pilosula in Breast Cancer: A Synergistic Approach Combining Network Pharmacology,Molecular Docking, and Machine Learning Techniques — Haodong Guo, Jie Li, et al. · Current Computer - Aided Drug Design (2026) | TGRS Research Map | TGRS