Maresin 1 promotes resolution of inflammation and improves left ventricle function in acute heart failure

High-dose maresin 1 activates FPR2 signalling and enhances the resolution of inflammation by modulating leukocyte dynamics and macrophage phenotype. Improving cardiac function and attenuating cardiorenal inflammation, highlighting the therapeutic potential of maresin 1 in cardiac healing and acute heart failure.

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Publication Details

Journal
British Journal of Pharmacology
Published
2026-01-15
DOI
https://doi.org/10.1111/bph.70318
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Maresin 1 promotes resolution of inflammation and improves left ventricle function in acute heart failure

Alexander Staruschenko, Ganesh V. Halade, Kevin A. Ingle, Shahriare Hossain et al.
British Journal of Pharmacology
Adipokines, Inflammation, and Metabolic Diseases
article

Maresin 1 promotes resolution of inflammation and improves left ventricle function in acute heart failure

Alexander Staruschenko, Ganesh V. Halade, Kevin A. Ingle, Shahriare Hossain, Vasundhara Kain, Romain A. Travis
article en

Abstract

High-dose maresin 1 activates FPR2 signalling and enhances the resolution of inflammation by modulating leukocyte dynamics and macrophage phenotype. Improving cardiac function and attenuating cardiorenal inflammation, highlighting the therapeutic potential of maresin 1 in cardiac healing and acute heart failure.

British Journal of Pharmacology
University of South Florida (US), University of Alabama at Birmingham (US), James A. Haley Veterans' Hospital (US)
Good health and well-being
Openalex Percentile: Top 86%
Adipokines, Inflammation, and Metabolic Diseases
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Maresin 1 promotes resolution of inflammation and improves left ventricle function in acute heart failure — Alexander Staruschenko, Ganesh V. Halade, et al. · British Journal of Pharmacology (2026) | TGRS Research Map | TGRS