Determinants of Early Atherosclerotic Changes in Adults with Growth Hormone Deficiency Receiving Replacement Therapy: A Cross-sectional Analysis of Intima-media Thickness and Endothelial Function

In long-term GHRT-treated patients, cIMT is linked to well-established cardiovascular risk factors rather than features of the pituitary disorder and its management, highlighting the need for targeted cardiovascular risk management alongside GHRT in AGHD.

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Publication Details

Journal
Current Vascular Pharmacology
Published
2026-01-15
DOI
https://doi.org/10.2174/0115701611413426251202060649
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
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article

Determinants of Early Atherosclerotic Changes in Adults with Growth Hormone Deficiency Receiving Replacement Therapy: A Cross-sectional Analysis of Intima-media Thickness and Endothelial Function

Andrej Janež, T. Kocjan, Ana Klinc, Rok Herman et al.
Current Vascular Pharmacology
Growth Hormone and Insulin-like Growth Factors
article

Determinants of Early Atherosclerotic Changes in Adults with Growth Hormone Deficiency Receiving Replacement Therapy: A Cross-sectional Analysis of Intima-media Thickness and Endothelial Function

Andrej Janež, T. Kocjan, Ana Klinc, Rok Herman, Mojca Jensterle
article en

Abstract

In long-term GHRT-treated patients, cIMT is linked to well-established cardiovascular risk factors rather than features of the pituitary disorder and its management, highlighting the need for targeted cardiovascular risk management alongside GHRT in AGHD.

Current Vascular PharmacologyVol. 24
University of Ljubljana (SI), Ljubljana University Medical Centre (SI)
Good health and well-being
Openalex Percentile: Top 86%
Growth Hormone and Insulin-like Growth Factors
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