Case Report: Fulminant shock due to PVL-positive Staphylococcus aureus in an adolescent—superantigen-negative sepsis with toxic shock-like features

PVL-positive <i>S. aureus</i> can, albeit rarely, be associated with an extreme toxic shock-like phenotype even when classical toxin genes are not detected. This case highlights the diagnostic and management challenges posed by atypical presentations and mixed shock physiology, and underscores the need for early recognition and rapid escalation of supportive care.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-16
DOI
https://doi.org/10.3389/fmed.2026.1729510
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: Fulminant shock due to PVL-positive Staphylococcus aureus in an adolescent—superantigen-negative sepsis with toxic shock-like features

Leonel Barreto Gutierrez, Rachid Attou, Evelyne Maillart, Sohaïb Mansour et al.
Frontiers in Medicine
Antimicrobial Resistance in Staphylococcus
article

Case Report: Fulminant shock due to PVL-positive Staphylococcus aureus in an adolescent—superantigen-negative sepsis with toxic shock-like features

Leonel Barreto Gutierrez, Rachid Attou, Evelyne Maillart, Sohaïb Mansour, Ayoub Jaafari
article en

Abstract

PVL-positive <i>S. aureus</i> can, albeit rarely, be associated with an extreme toxic shock-like phenotype even when classical toxin genes are not detected. This case highlights the diagnostic and management challenges posed by atypical presentations and mixed shock physiology, and underscores the need for early recognition and rapid escalation of supportive care.

Frontiers in MedicineVol. 13
Centre Hospitalier Universitaire Brugmann (BE)
Good health and well-being
Openalex Percentile: Top 84%
Antimicrobial Resistance in Staphylococcus
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