Case Report: Fulminant shock due to PVL-positive Staphylococcus aureus in an adolescent—superantigen-negative sepsis with toxic shock-like features
PVL-positive <i>S. aureus</i> can, albeit rarely, be associated with an extreme toxic shock-like phenotype even when classical toxin genes are not detected. This case highlights the diagnostic and management challenges posed by atypical presentations and mixed shock physiology, and underscores the need for early recognition and rapid escalation of supportive care.
Authors
- Leonel Barreto Gutierrez
- Rachid Attou (ORCID: https://orcid.org/0000-0002-0156-3628)
- Evelyne Maillart (ORCID: https://orcid.org/0000-0002-5354-068X)
- Sohaïb Mansour (ORCID: https://orcid.org/0009-0008-5314-6026)
- Ayoub Jaafari
Institutions
- Centre Hospitalier Universitaire Brugmann (BE)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fmed.2026.1729510
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00