Three‐Component Cascade Cyclization of Nitrones, Arylsulfonyl Azides, and Isocyanides for Synthesis of 5‐Imino‐1,2,4‐Oxadiazolidines
Under the catalysis of Pd 2 (dba) 3 (10 mol%) and phosphoramidite (±)‐ L13 (20 mol%) in 1,2‐DCE at 80°C, the three‐component cascade cyclization of nitrones, arylsulfonyl azides, and isocyanides proceeded readily and delivered 5‐imino‐1,2,4‐oxadiazolidines in reasonable chemical yields. The chemical structure of one title compound has been confirmed by X‐ray diffraction analysis, and the others are suggested by inference.
Authors
- KUO CHEN WANG
- He Zhao (ORCID: https://orcid.org/0000-0002-3551-1455)
- Shun‐Xin Zhang (ORCID: https://orcid.org/0000-0002-5936-164X)
- Kuo Wang (ORCID: https://orcid.org/0000-0001-9537-0167)
- Yu‐Hang Mi
- Zhang Ye (ORCID: https://orcid.org/0000-0003-3495-5596)
- Xian‐Yi Huang
- Ya‐Hui Wang
- Ya‐Qi Yang
Institutions
- Beijing University of Technology (CN)
- Beijing University of Chemical Technology (CN)
- University of Science and Technology Beijing (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1002/ejoc.202501126
- Primary Topic
- Click Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing University of Technology
- Funding Project for Academic Human Resources Development in Institutions of Higher Learning under the Jurisdiction of Beijing Municipality