Obstructive Jaundice Revealing Primary Diffuse Large B-Cell Lymphoma of the Ampulla of Vater in a Child: A Case Report

This case underscores that lymphoma, though rare, should be considered in the differential diagnosis of obstructive jaundice even in children. A multimodal approach involving ERCP with biopsy and imperative immunohistochemistry is crucial for an accurate diagnosis to avoid unnecessary surgery. Management centered on immunochemotherapy, with adjuncts like biliary decompression and radiotherapy, can lead to successful outcomes in pediatric ampullary DLBCL.

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Publication Details

Journal
Case Reports in Oncology
Published
2026-01-16
DOI
https://doi.org/10.1159/000550534
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Obstructive Jaundice Revealing Primary Diffuse Large B-Cell Lymphoma of the Ampulla of Vater in a Child: A Case Report

Maher Saifo, Ahmad Al-Bitar
Case Reports in Oncology
Lymphoma Diagnosis and Treatment
article

Obstructive Jaundice Revealing Primary Diffuse Large B-Cell Lymphoma of the Ampulla of Vater in a Child: A Case Report

Maher Saifo, Ahmad Al-Bitar
article en

Abstract

This case underscores that lymphoma, though rare, should be considered in the differential diagnosis of obstructive jaundice even in children. A multimodal approach involving ERCP with biopsy and imperative immunohistochemistry is crucial for an accurate diagnosis to avoid unnecessary surgery. Management centered on immunochemotherapy, with adjuncts like biliary decompression and radiotherapy, can lead to successful outcomes in pediatric ampullary DLBCL.

Case Reports in OncologyVol. 19(1)
Damascus University (SY)
Good health and well-being
Openalex Percentile: Top 86%
Lymphoma Diagnosis and Treatment
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