Predictive value of serum IGFBP-3 and transvaginal cervical length measurement for spontaneous preterm birth in singleton pregnancies: a prospective study

The use of serum IGFBP-3 levels in combination with cervical length had a good sensitivity to predict preterm birth. While NPV is high, the low PPV limits its standalone use to predict preterm birth.

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Publication Details

Journal
The Journal of Maternal-Fetal & Neonatal Medicine
Published
2026-01-15
DOI
https://doi.org/10.1080/14767058.2026.2614836
Primary Topic
Preterm Birth and Chorioamnionitis
Type
article
Field-Weighted Citation Impact
0.00
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article

Predictive value of serum IGFBP-3 and transvaginal cervical length measurement for spontaneous preterm birth in singleton pregnancies: a prospective study

V. Phupong, Supakit Mhernchan
The Journal of Maternal-Fetal & Neonatal Medicine
Preterm Birth and Chorioamnionitis
article

Predictive value of serum IGFBP-3 and transvaginal cervical length measurement for spontaneous preterm birth in singleton pregnancies: a prospective study

V. Phupong, Supakit Mhernchan
article en

Abstract

The use of serum IGFBP-3 levels in combination with cervical length had a good sensitivity to predict preterm birth. While NPV is high, the low PPV limits its standalone use to predict preterm birth.

The Journal of Maternal-Fetal & Neonatal MedicineVol. 39(1)
Chulalongkorn University (TH)
Openalex Percentile: Top 86%
Preterm Birth and Chorioamnionitis
DOIOpen Access PDFOpenAlex
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Predictive value of serum IGFBP-3 and transvaginal cervical length measurement for spontaneous preterm birth in singleton pregnancies: a prospective study — V. Phupong, Supakit Mhernchan · The Journal of Maternal-Fetal & Neonatal Medicine (2026) | TGRS Research Map | TGRS