ATF3 Mediates the Immunoregulatory Role of the Tim‐3 Pathway in Primary Biliary Cholangitis

These findings highlight the prominent pro-inflammatory innate immune response in PBC patients and demonstrate that ATF3 partially mediates the immunomodulatory effects of the Tim-3/Galectin-9 pathway on macrophages.

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Publication Details

Journal
Journal of Gastroenterology and Hepatology
Published
2026-01-15
DOI
https://doi.org/10.1111/jgh.70234
Primary Topic
Galectins and Cancer Biology
Type
article
Field-Weighted Citation Impact
0.00
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article

ATF3 Mediates the Immunoregulatory Role of the Tim‐3 Pathway in Primary Biliary Cholangitis

Haitao Ma, Jiamin Xu, Wenxia Yang, Yingmei Tang et al.
Journal of Gastroenterology and Hepatology
Galectins and Cancer Biology
article

ATF3 Mediates the Immunoregulatory Role of the Tim‐3 Pathway in Primary Biliary Cholangitis

Haitao Ma, Jiamin Xu, Wenxia Yang, Yingmei Tang, Rongfang Tu, Yang Feng, Simiao Li, Weimin Bao, Hua Lin
article en

Abstract

These findings highlight the prominent pro-inflammatory innate immune response in PBC patients and demonstrate that ATF3 partially mediates the immunomodulatory effects of the Tim-3/Galectin-9 pathway on macrophages.

Journal of Gastroenterology and HepatologyVol. 41(2)
Yunnan University (CN), Kunming Medical University (CN), First People's Hospital of Yunnan Province (CN), Yunnan Center for Disease Control And Prevention (CN)
Openalex Percentile: Top 86%
Galectins and Cancer Biology
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