Clinicopathologic and Immunohistochemical Features of Enfortumab Vedotin‐Induced Cutaneous Toxicity

Intercellular IgG on routine immunohistochemistry, together with characteristic "ring" mitoses, provides a practical framework to identify enfortumab vedotin-associated eruptions and differentiate them from erythema multiforme and SJS/TEN.

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Publication Details

Journal
International Journal of Dermatology
Published
2026-01-15
DOI
https://doi.org/10.1111/ijd.70258
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

Clinicopathologic and Immunohistochemical Features of Enfortumab Vedotin‐Induced Cutaneous Toxicity

Eudora Lee, Mai P. Hoang, Federico Repetto, Yevgeniy R. Semenov et al.
International Journal of Dermatology
Drug-Induced Adverse Reactions
article

Clinicopathologic and Immunohistochemical Features of Enfortumab Vedotin‐Induced Cutaneous Toxicity

Eudora Lee, Mai P. Hoang, Federico Repetto, Yevgeniy R. Semenov, Soma Jobbagy, Rosalynn M Nazarian, May P. Chan, Eleanor E. Russell‐Goldman
article en

Abstract

Intercellular IgG on routine immunohistochemistry, together with characteristic "ring" mitoses, provides a practical framework to identify enfortumab vedotin-associated eruptions and differentiate them from erythema multiforme and SJS/TEN.

International Journal of Dermatology
Brigham and Women's Hospital (US), Harvard University (US), Massachusetts General Hospital (US), Michigan Medicine (US)
Openalex Percentile: Top 84%
Drug-Induced Adverse Reactions
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