Autoimmune encephalitis associated with antibodies against intracellular antigens in children

In AE associated with Abs against intracellular antigens of children, seizures were the most common clinical manifestation. For patients with seizures without obvious inducement or suspected encephalitis, AE-related Abs should be detected promptly, and immunosuppressive therapy should be administered as early as possible. The prognosis of pediatric patients with encephalitis with Abs differs from that in adults, and most patients recover well after active treatment.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-16
DOI
https://doi.org/10.3389/fimmu.2025.1678497
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Autoimmune encephalitis associated with antibodies against intracellular antigens in children

Zhang Lq, Chao Che, Xingyu Han, Aihua Cao
Frontiers in Immunology
Autoimmune Neurological Disorders and Treatments
article

Autoimmune encephalitis associated with antibodies against intracellular antigens in children

Zhang Lq, Chao Che, Xingyu Han, Aihua Cao
article en

Abstract

In AE associated with Abs against intracellular antigens of children, seizures were the most common clinical manifestation. For patients with seizures without obvious inducement or suspected encephalitis, AE-related Abs should be detected promptly, and immunosuppressive therapy should be administered as early as possible. The prognosis of pediatric patients with encephalitis with Abs differs from that in adults, and most patients recover well after active treatment.

Frontiers in ImmunologyVol. 16
Qilu Hospital of Shandong University (CN)
National Natural Science Foundation of China
No poverty
Openalex Percentile: Top 86%
Autoimmune Neurological Disorders and Treatments
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