<i>JAMA</i> : Older adults still face risks despite CNS drug decline

Despite a steady decline in prescribing potentially inappropriate central nervous system (CNS)–active medications for older adults in recent years, concerns remain about their continued use and associated risks, according to new research in JAMA , published Jan. 12. Patients with cognitive impairment were more likely than those with normal cognition to receive such medications. Researchers also found that more than two‐thirds of these prescriptions lacked any documented clinical indication.

Authors

Publication Details

Journal
Mental Health Weekly
Published
2026-01-16
DOI
https://doi.org/10.1002/mhw.34726
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

JAMA : Older adults still face risks despite CNS drug decline

Valerie A. Canady
Mental Health Weekly
Dementia and Cognitive Impairment Research
article

JAMA : Older adults still face risks despite CNS drug decline

Valerie A. Canady
article en

Abstract

Despite a steady decline in prescribing potentially inappropriate central nervous system (CNS)–active medications for older adults in recent years, concerns remain about their continued use and associated risks, according to new research in JAMA , published Jan. 12. Patients with cognitive impairment were more likely than those with normal cognition to receive such medications. Researchers also found that more than two‐thirds of these prescriptions lacked any documented clinical indication.

Mental Health WeeklyVol. 36(3)
Good health and well-being
Openalex Percentile: Top 86%
Dementia and Cognitive Impairment Research
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<i>JAMA</i> : Older adults still face risks despite CNS drug decline — Valerie A. Canady · Mental Health Weekly (2026) | TGRS Research Map | TGRS