Diagnostic efficacy of blood biomarkers for differentiating early-stage pancreatic cancer from chronic pancreatitis: A systematic review and network meta-analysis

CA199 demonstrated only moderate diagnostic discrimination between PC and CP, with reduced efficacy in early-stage PC. Combining CA199 and eight exLRs exhibited promising differential diagnostic efficacy with both high sensitivity and specificity.

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Publication Details

Journal
Translational Oncology
Published
2026-01-16
DOI
https://doi.org/10.1016/j.tranon.2026.102674
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic efficacy of blood biomarkers for differentiating early-stage pancreatic cancer from chronic pancreatitis: A systematic review and network meta-analysis

Zhu Yp, Yi Zheng, Di Wu, Zhimin Du et al.
Translational Oncology
Pancreatitis Pathology and Treatment
article

Diagnostic efficacy of blood biomarkers for differentiating early-stage pancreatic cancer from chronic pancreatitis: A systematic review and network meta-analysis

Zhu Yp, Yi Zheng, Di Wu, Zhimin Du, Cao Yu, Yanru Wang, Lei Wang, Hang-Ming Qi, Zhuan Liao, Wen-Bin Zou
article en

Abstract

CA199 demonstrated only moderate diagnostic discrimination between PC and CP, with reduced efficacy in early-stage PC. Combining CA199 and eight exLRs exhibited promising differential diagnostic efficacy with both high sensitivity and specificity.

Translational OncologyVol. 65
Second Military Medical University (CN), Changhai Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 86%
Pancreatitis Pathology and Treatment
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