Dihydropyrimidine dehydrogenase testing: capturing what standard genotyping misses with next-generation sequencing
NGS analysis enables the identification of <i>DPYD</i> rare or structural variants with potential functional impact, thereby improving the genetic assessment of DPD deficiency.
Authors
- C. Tron
- Nicolas Picard (ORCID: https://orcid.org/0000-0002-5572-9419)
- Dorian Chastagner
- Mohamed Ksentini
- Maxime Sourdioux
Institutions
- Université Rennes 2 (FR)
- Centre Hospitalier Universitaire de Limoges (FR)
- Centre Hospitalier Universitaire de Rennes (FR)
- Université de Rennes (FR)
- Université de Limoges (FR)
Publication Details
- Journal
- Pharmacogenomics
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1080/14622416.2026.2613869
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00