Chondroid Lipoma Arising over the Plantar Aspect of Right Foot: A Case Report

Chondroid lipoma is a rare benign soft-tissue tumour characterised by the presence of both mature adipose and chondroid-like extracellular matrix components. We present the case of a 34-year-old male who reported a slow-growing, painless swelling on the plantar aspect of the right foot evolving over two years, with a history of preceding trauma. The swelling was associated with sharp, pricking pain exacerbated by walking and relieved on rest in the last eight months. The patient had no similar lesions elsewhere and was newly diagnosed with diabetes without other comorbidities. Clinical evaluation and imaging are crucial for diagnosis, given the rarity and non-specific presentation of this tumour, especially at the uncommon plantar foot location, which can mimic other soft tissue masses. Magnetic Resonance Imaging (MRI) plays a significant role in delineating the tumour's extent and composition, aiding in surgical planning. Histopathological examination confirms the diagnosis by revealing a biphasic pattern of mature adipocytes mixed with chondroid areas devoid of malignant features. Complete surgical excision is the treatment of choice, with an excellent prognosis and a low likelihood of recurrence. This case underscores the importance of considering chondroid lipoma in the differential diagnosis of slow-growing, painful swellings in the foot, especially post-trauma, to avoid misdiagnosis and ensure appropriate management. Awareness of this rare entity enables clinicians to differentiate it from more aggressive neoplasms and tailor treatment accordingly, leading to better patient outcomes.

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2026-01-16
DOI
https://doi.org/10.7860/jcdr/2026/82981.22577
Primary Topic
Sarcoma Diagnosis and Treatment
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article
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article

Chondroid Lipoma Arising over the Plantar Aspect of Right Foot: A Case Report

Muthu Sudalaimuthu, Vishnu Prakasam, Anish Chandran, Sushma Pabbisetty et al.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Sarcoma Diagnosis and Treatment
article

Chondroid Lipoma Arising over the Plantar Aspect of Right Foot: A Case Report

Muthu Sudalaimuthu, Vishnu Prakasam, Anish Chandran, Sushma Pabbisetty, Ramya Banage
article en

Abstract

Chondroid lipoma is a rare benign soft-tissue tumour characterised by the presence of both mature adipose and chondroid-like extracellular matrix components. We present the case of a 34-year-old male who reported a slow-growing, painless swelling on the plantar aspect of the right foot evolving over two years, with a history of preceding trauma. The swelling was associated with sharp, pricking pain exacerbated by walking and relieved on rest in the last eight months. The patient had no similar lesions elsewhere and was newly diagnosed with diabetes without other comorbidities. Clinical evaluation and imaging are crucial for diagnosis, given the rarity and non-specific presentation of this tumour, especially at the uncommon plantar foot location, which can mimic other soft tissue masses. Magnetic Resonance Imaging (MRI) plays a significant role in delineating the tumour's extent and composition, aiding in surgical planning. Histopathological examination confirms the diagnosis by revealing a biphasic pattern of mature adipocytes mixed with chondroid areas devoid of malignant features. Complete surgical excision is the treatment of choice, with an excellent prognosis and a low likelihood of recurrence. This case underscores the importance of considering chondroid lipoma in the differential diagnosis of slow-growing, painful swellings in the foot, especially post-trauma, to avoid misdiagnosis and ensure appropriate management. Awareness of this rare entity enables clinicians to differentiate it from more aggressive neoplasms and tailor treatment accordingly, leading to better patient outcomes.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
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