Case Report: Personalized, functional drug sensitivity-guided chemotherapy achieves long-term disease-free survival in canine pulmonary adenocarcinoma
This case highlights the clinical utility of integrating functional drug sensitivity testing and organoid validation into personalized chemotherapy decision-making for canine PAC, demonstrating prolonged disease-free survival exceeding 500 days in a patient with intermediate-grade histology and suspected nodal involvement.
Authors
- Kyu-Duk Yeon (ORCID: https://orcid.org/0009-0003-3442-8216)
- Jung Hyun Kim (ORCID: https://orcid.org/0000-0001-7484-7739)
- Kieun Bae
- Jin-Young Choi
Institutions
- Konkuk University (KR)
- Konkuk University Medical Center (KR)
- The Schwarzman Animal Medical Center (US)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fvets.2025.1678271
- Primary Topic
- Veterinary Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Konkuk University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea