3D analysis of age-related compensation of retinal capillary plexuses in normal population via wide-field volume-mode SS-OCTA: Focus on interlayer connecting branches

Normal RCP has an age-related compensatory mechanism: "sacrificing peripheral blood flow to protect macular blood flow". This compensation is supported by interlayer branch changes: vertical branches decrease while oblique branches become relatively dominant. It maintains macular blood flow and central vision, helping distinguish normal aging from pathological vascular damage.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2026-01-15
DOI
https://doi.org/10.1016/j.pdpdt.2026.105350
Primary Topic
Retinal and Macular Surgery
Type
article
Field-Weighted Citation Impact
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article

3D analysis of age-related compensation of retinal capillary plexuses in normal population via wide-field volume-mode SS-OCTA: Focus on interlayer connecting branches

Liang Yao, Nianjia Wang, Juan Ye, Meizhu Wang et al.
Photodiagnosis and Photodynamic Therapy
Retinal and Macular Surgery
article

3D analysis of age-related compensation of retinal capillary plexuses in normal population via wide-field volume-mode SS-OCTA: Focus on interlayer connecting branches

Liang Yao, Nianjia Wang, Juan Ye, Meizhu Wang, Menglu Chen, Qi Gao, Xindi Liu
article en

Abstract

Normal RCP has an age-related compensatory mechanism: "sacrificing peripheral blood flow to protect macular blood flow". This compensation is supported by interlayer branch changes: vertical branches decrease while oblique branches become relatively dominant. It maintains macular blood flow and central vision, helping distinguish normal aging from pathological vascular damage.

Photodiagnosis and Photodynamic TherapyVol. 57
Wenzhou Medical University (CN), Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN), Second Affiliated Hospital of Xi'an Jiaotong University (CN), Second Affiliated Hospital of Zhejiang University (CN)
Openalex Percentile: Top 87%
Retinal and Macular Surgery
DOIOpen Access PDFOpenAlex
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3D analysis of age-related compensation of retinal capillary plexuses in normal population via wide-field volume-mode SS-OCTA: Focus on interlayer connecting branches — Liang Yao, Nianjia Wang, et al. · Photodiagnosis and Photodynamic Therapy (2026) | TGRS Research Map | TGRS