Monoclonal antibodies for Mpox: protective targets and therapeutic potential
This review summarizes the major antibody targets identified in MPXV, recent advances in understanding antibody-mediated neutralization and protection, and how the therapeutic potential of antibodies can be leveraged to treat mpox and other orthopoxvirus infections as well as to guide the design of effective antiorthopoxvirus vaccines.
Authors
- Pablo Guardado‐Calvo (ORCID: https://orcid.org/0000-0001-7292-5270)
- Natalia T. Freund (ORCID: https://orcid.org/0000-0002-5386-502X)
- Camila H. Coelho (ORCID: https://orcid.org/0000-0002-7885-9996)
Institutions
- Institut Pasteur (FR)
- Tel Aviv University (IL)
- Université Paris Cité (FR)
- Mental Illness Research, Education and Clinical Centers (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Current Opinion in HIV and AIDS
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1097/coh.0000000000001014
- Citations
- 1
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 27.20