Association of serum 25-hydroxyvitamin D and homocysteine “double-risk” status with executive dysfunction in older adults with hypertension

In older hypertensive inpatients, lower 25(OH)D and higher homocysteine are non-linearly associated with executive dysfunction, and co-occurrence confers excess risk beyond individual effects. Assessing both biomarkers may enhance risk stratification and guide trials of combined correction.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-01-16
DOI
https://doi.org/10.3389/fnut.2025.1718923
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of serum 25-hydroxyvitamin D and homocysteine “double-risk” status with executive dysfunction in older adults with hypertension

Hongyan Li, Yamin Zhao, Linya Zhao, Lili Tan et al.
Frontiers in Nutrition
Vitamin D Research Studies
article

Association of serum 25-hydroxyvitamin D and homocysteine “double-risk” status with executive dysfunction in older adults with hypertension

Hongyan Li, Yamin Zhao, Linya Zhao, Lili Tan, Yinyin Chen
article en

Abstract

In older hypertensive inpatients, lower 25(OH)D and higher homocysteine are non-linearly associated with executive dysfunction, and co-occurrence confers excess risk beyond individual effects. Assessing both biomarkers may enhance risk stratification and guide trials of combined correction.

Frontiers in NutritionVol. 12
Affiliated Hospital of Hebei University (CN)
Baoding City Science and Technology and Intellectual Property Bureau
Openalex Percentile: Top 86%
Vitamin D Research Studies
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