Diagnostic value of combined detection of cryptococcal antigen in serum and lung puncture fluid using lateral flow assay for diagnosing pulmonary cryptococcosis: a single-center prospective study
Serum CrAg testing has superior sensitivity and accuracy compared to the conventional cryptococcal culture method using LPF, and CrAg testing of LPF samples further enhances diagnostic sensitivity. Moreover, detecting CrAg in serum and LPF specimens together provides high sensitivity and specificity, which significantly improves the diagnostic efficiency of PC.
Authors
- Xinchen Lin (ORCID: https://orcid.org/0000-0002-1465-5628)
- Heng Weng (ORCID: https://orcid.org/0000-0003-0945-2153)
- YangYu Li
- Ling Ye (ORCID: https://orcid.org/0000-0003-0903-9377)
- Meiqin Jiang
- Jinbao Huang (ORCID: https://orcid.org/0000-0002-1248-0019)
- Li Ha
- Shungui Xu
- Li Wang
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fmicb.2025.1747123
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangzhou Medical University