Exploration of circadian rhythm characteristics and its impact on prognosis and neuroinflammation in acute ischemic stroke patients

In mild AIS patients, the endogenous melatonin secretion peak decreased, and the time to reach the peak was delayed. A delayed endogenous circadian rhythm might be an independent risk factor for poor prognosis in mild AIS patients, and HIF-1α might be involved in this process.

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Publication Details

Journal
Neurological Research
Published
2026-01-16
DOI
https://doi.org/10.1080/01616412.2026.2614348
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploration of circadian rhythm characteristics and its impact on prognosis and neuroinflammation in acute ischemic stroke patients

Sheng-nan Chen, Yue Ding, Cean Guo, Qian Sun et al.
Neurological Research
Circadian rhythm and melatonin
article

Exploration of circadian rhythm characteristics and its impact on prognosis and neuroinflammation in acute ischemic stroke patients

Sheng-nan Chen, Yue Ding, Cean Guo, Qian Sun, Jie Li, Rui Chen
article en

Abstract

In mild AIS patients, the endogenous melatonin secretion peak decreased, and the time to reach the peak was delayed. A delayed endogenous circadian rhythm might be an independent risk factor for poor prognosis in mild AIS patients, and HIF-1α might be involved in this process.

Neurological Research
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN)
No poverty
Openalex Percentile: Top 85%
Circadian rhythm and melatonin
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