Effectiveness of transcranial electrical stimulation combined with dual-task training in stroke, mild cognitive impairment and Parkinson’s disease: a systematic review and meta-analysis of randomized controlled trials

The meta-analysis suggests that the effects of tDCS combined with DTT are remarkable in certain populations and for specific outcomes. While substantial improvements are confirmed for executive function and dual-task gait in MCI and stroke, the overall limited efficacy in PD highlights the critical influence of heterogeneity and intervention specificity. Future research should prioritize disease-specific electrode montages and the integration of tACS or tRNS to optimize outcomes across diverse neurological populations.

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Publication Details

Journal
Frontiers in Human Neuroscience
Published
2026-01-16
DOI
https://doi.org/10.3389/fnhum.2025.1688110
Primary Topic
Transcranial Magnetic Stimulation Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Effectiveness of transcranial electrical stimulation combined with dual-task training in stroke, mild cognitive impairment and Parkinson’s disease: a systematic review and meta-analysis of randomized controlled trials

Lin Yao, Siaw Chui Chai, Chang Zhu, Yutong Fu et al.
Frontiers in Human Neuroscience
Transcranial Magnetic Stimulation Studies
article

Effectiveness of transcranial electrical stimulation combined with dual-task training in stroke, mild cognitive impairment and Parkinson’s disease: a systematic review and meta-analysis of randomized controlled trials

Lin Yao, Siaw Chui Chai, Chang Zhu, Yutong Fu, Ponnusamy Subramaniam, Qianxi Yan, Devinder Kaur Ajit Singh, Wenli Wang
article en

Abstract

The meta-analysis suggests that the effects of tDCS combined with DTT are remarkable in certain populations and for specific outcomes. While substantial improvements are confirmed for executive function and dual-task gait in MCI and stroke, the overall limited efficacy in PD highlights the critical influence of heterogeneity and intervention specificity. Future research should prioritize disease-specific electrode montages and the integration of tACS or tRNS to optimize outcomes across diverse neurological populations.

Frontiers in Human NeuroscienceVol. 19
Kunming Medical University (CN), National University of Malaysia (MY)
Kunming Medical University
Quality Education
Openalex Percentile: Top 89%
Transcranial Magnetic Stimulation Studies
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Effectiveness of transcranial electrical stimulation combined with dual-task training in stroke, mild cognitive impairment and Parkinson’s disease: a systematic review and meta-analysis of randomized controlled trials — Lin Yao, Siaw Chui Chai, et al. · Frontiers in Human Neuroscience (2026) | TGRS Research Map | TGRS