Assessment of T1 and T2 relaxation times of deuterium (2H) labeled resonances in the human liver and kidney using k-space reordered 3D concentric ring trajectory sampling at 7T

Hepatic and renal glucose homeostasis is often impaired in several pathophysiological conditions such as tumors, diabetes and metabolic dysfunction-associated steatotic liver disease. Using organ-specific <sup>2</sup>H relaxation times increases the accuracy of concentration estimation and can help to improve the understanding of underlying metabolic processes in future abdominal DMI studies, which can help to push abdominal DMI towards clinical application.

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Publication Details

Journal
Magnetic Resonance Materials in Physics Biology and Medicine
Published
2026-01-16
DOI
https://doi.org/10.1007/s10334-025-01320-9
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Assessment of T1 and T2 relaxation times of deuterium (2H) labeled resonances in the human liver and kidney using k-space reordered 3D concentric ring trajectory sampling at 7T

Martin Krššák, Wolfgang Bogner, Lukas Hingerl, Fabian Niess et al.
Magnetic Resonance Materials in Physics Biology and Medicine
Advanced MRI Techniques and Applications
article

Assessment of T1 and T2 relaxation times of deuterium (2H) labeled resonances in the human liver and kidney using k-space reordered 3D concentric ring trajectory sampling at 7T

Martin Krššák, Wolfgang Bogner, Lukas Hingerl, Fabian Niess, Thomas Scherer, Bernhard Strasser, Lorenz Pfleger, Anna Duguid, J Kovarík, Viola Bader, Sabina Frese, Aaron Osburg
article en

Abstract

Hepatic and renal glucose homeostasis is often impaired in several pathophysiological conditions such as tumors, diabetes and metabolic dysfunction-associated steatotic liver disease. Using organ-specific <sup>2</sup>H relaxation times increases the accuracy of concentration estimation and can help to improve the understanding of underlying metabolic processes in future abdominal DMI studies, which can help to push abdominal DMI towards clinical application.

Magnetic Resonance Materials in Physics Biology and Medicine
Austrian Research Institute for Artificial Intelligence (AT), Comprehensive Cancer Center Vienna (AT), Medical University of Vienna (AT)
Österreichische Nationalstiftung für Forschung, Technologie und Entwicklung, European Commission, Austrian Science Fund, Universität Wien, Medizinische Universität Wien, Christian Doppler Forschungsgesellschaft, Bundesministerium für Digitalisierung und Wirtschaftsstandort, National Institutes of Health
Openalex Percentile: Top 87%
Advanced MRI Techniques and Applications
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