The Diagnostic Value of Image-Based Machine Learning for Osteoporosis: Systematic Review and Meta-Analysis

ML based on medical imaging demonstrates high diagnosis accuracy for OP, particularly DL models using x-ray and CT modalities. However, this study included only a limited number of original studies using MRI-based ML, and there remains a lack of adequate external validation across studies, which poses interpretative limitations. Future research should aim to develop artificial intelligence tools with broader applicability and enhanced diagnostic precision.

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Publication Details

Journal
Journal of Medical Internet Research
Published
2026-01-16
DOI
https://doi.org/10.2196/75965
Primary Topic
Bone health and osteoporosis research
Type
article
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article

The Diagnostic Value of Image-Based Machine Learning for Osteoporosis: Systematic Review and Meta-Analysis

Yu Liu, Rui Zhao, Yanping Lin, Jiachun Huang et al.
Journal of Medical Internet Research
Bone health and osteoporosis research
article

The Diagnostic Value of Image-Based Machine Learning for Osteoporosis: Systematic Review and Meta-Analysis

Yu Liu, Rui Zhao, Yanping Lin, Jiachun Huang, Zhijie Yang, Hongxing Huang, Lei Wan, Haolin Yang, Yangbo Li
article en

Abstract

ML based on medical imaging demonstrates high diagnosis accuracy for OP, particularly DL models using x-ray and CT modalities. However, this study included only a limited number of original studies using MRI-based ML, and there remains a lack of adequate external validation across studies, which poses interpretative limitations. Future research should aim to develop artificial intelligence tools with broader applicability and enhanced diagnostic precision.

Journal of Medical Internet ResearchVol. 28
Guangzhou University of Chinese Medicine (CN), The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine (CN)
Quality Education
Openalex Percentile: Top 87%
Bone health and osteoporosis research
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The Diagnostic Value of Image-Based Machine Learning for Osteoporosis: Systematic Review and Meta-Analysis — Yu Liu, Rui Zhao, et al. · Journal of Medical Internet Research (2026) | TGRS Research Map | TGRS