Acidemia predicts mortality independently of lactate levels in patients after cardiac arrest

Post-cardiac-arrest acidemia is associated with higher mortality independently of lactate, ventilation, or CPR characteristics. Among hospital survivors, admission pH was not significantly associated with neurological outcome. These findings support pH as an early marker for mortality risk stratification after cardiac arrest, to be interpreted in the context of multimodal prognostication.

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Publication Details

Journal
Resuscitation Plus
Published
2026-01-16
DOI
https://doi.org/10.1016/j.resplu.2026.101234
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
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article

Acidemia predicts mortality independently of lactate levels in patients after cardiac arrest

Dragos Andrei Duse, Ralf Erkens, P. Horn, Matthias Ortkemper et al.
Resuscitation Plus
Cardiac Arrest and Resuscitation
article

Acidemia predicts mortality independently of lactate levels in patients after cardiac arrest

Dragos Andrei Duse, Ralf Erkens, P. Horn, Matthias Ortkemper, Andreea Ganea, Jafer Haschemi, Christian Jung, Malte Kelm, Philipp Defke
article en

Abstract

Post-cardiac-arrest acidemia is associated with higher mortality independently of lactate, ventilation, or CPR characteristics. Among hospital survivors, admission pH was not significantly associated with neurological outcome. These findings support pH as an early marker for mortality risk stratification after cardiac arrest, to be interpreted in the context of multimodal prognostication.

Resuscitation PlusVol. 28
Saint Agnes Hospital (US), University of Cologne (DE), Heinrich Heine University Düsseldorf (DE)
Good health and well-being
Openalex Percentile: Top 88%
Cardiac Arrest and Resuscitation
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