Magnesium(I)‐Mediated Dearomatizing Coupling of Pyridines and Subsequent Hydrogen Transfer Reactions
The Mg─Mg-bonded compound [K(THF)<sub>3</sub>]<sub>2</sub>[LMg─MgL]<sub>2</sub> (1, L = [(2,6-iPr<sub>2</sub>C<sub>6</sub>H<sub>3</sub>)NC(CH<sub>3</sub>)]<sub>2</sub> <sup>2-</sup>) can promote reductive 4,4'-homocoupling of pyridine and derivatives under ambient conditions, yielding the 4,4'-dihydro-4,4'-bipyridinate products 2-6. Interestingly, these species can be viewed as "dimerized" metal-1,4-dihydropyridinates (bis-M-DHPs) and can transfer hydrogen or deuterium (as proton and hydride) to pyridines, imines and alkenes. This may provide a facile access to new H/D-donors, readily obtained from commercially available pyridines and a conveniently synthesized magnesium(I) complex, for controllable H-transfer (HT) to different types of unsaturated molecules. The coupling and HT mechanisms were elucidated by DFT calculations.
Authors
- Xueping Yang (ORCID: https://orcid.org/0000-0002-9184-8116)
- Luomo Li
- Shi‐Lu Chen (ORCID: https://orcid.org/0000-0002-0783-0766)
- Lei Yang (ORCID: https://orcid.org/0000-0001-6357-2768)
- Zhenzhou Sun
- Biao Wu
Institutions
- Beijing Institute of Technology (CN)
- Ministry of Industry and Information Technology (CN)
Publication Details
- Journal
- Chemistry - A European Journal
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1002/chem.202503394
- Primary Topic
- Coordination Chemistry and Organometallics
- Type
- article
- Field-Weighted Citation Impact
- 0.00